A study by the International and American Associations for Dental Research found no significant association between bone fluoride levels and an osteosarcoma risk.

There has been an ongoing heated debate as to whether there is an association between fluoride and a risk for osteosarcoma.

As reported by Medical News Today, the study sample included incident cases of primary osteosarcoma and a control group of patients with newly-diagnosed malignant bone tumors. Specimens of tumor-adjacent bone and iliac crest bone were analyzed for fluoride content.

“The controversy over whether there is an association between fluoride and risk for osteosarcoma has existed since an inconclusive animal study 20 years ago,” said IADR Vice-president Helen Whelton. “Numerous human descriptive and case-control studies have attempted to address the controversy, but this study of using actual bone fluoride concentrations as a direct indicator of fluoride exposure represents our best science to date and shows no association between fluoride in bone and osteosarcoma risk.”

For more on this story see: Bone Fluoride Levels Not Associated With Osteosarcoma